Effects of Increased Protein Intake as a Variant of Rural Diet in Human Volunteers of Rural Bengal

Mukherjee, Sutapa and Dey, Baishakhi and Das, Shubhayan and Thakur, Goutam and Chakrobarty, Chandan (2015) Effects of Increased Protein Intake as a Variant of Rural Diet in Human Volunteers of Rural Bengal. xxx. pp. 1-14.

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Constant escalations in the number of diabetics’ worldwide, associated complications and financial implications, failure of conventional therapy regimen to restore normoglycemia has brought to limelight the non-pharmacologic means like lifestyle and dietary interventions as one of the effective aids to combat type 2 diabetes. Economy, education, preference plays a role in dietary selection. Prolonged intake of carbohydrate enriched diet was found to be a causative of diabetes amongst poor rural Indian population of Bengal. Contrastingly, current research of three years RCT amongst rural Bengalis have shown that a daily increase in protein intake by 25-30% when compared with standard rural diet comprising of about 70% to 80% of carbohydrate, 10% fats and 10% protein, improved insulin sensitivity and lowered fasting blood glucose level amongst experimental population significantly (p=0.04) rather than the control group. Fasting serum insulin value decreased from 47±2.2 pmol/l to 44±2.4 pmol/l (p=0.04) in the study group but amongst controls an increment from 42±2.4 pmol/l to 43±2.4 pmol/l was observed. Fasting Blood Sugar level amongst controls was initially 103±4 mg/dl and became 105±6 mg/dl but in the experimental group initial value of 109±12 mg/dl diminished to 103±8 mg/dl (p=0.04) at the end of 3 years follow up. However blood lipid parameters (TC, LDL, HDL, and VLDL) were not significantly influenced by higher daily protein intake both in control and experimental group. Thus a conclusive fact found from the trial is that protein enriched, low carbohydrate diet can offer a positive impact on glycemic control kidney functions remaining normal. (250 words)

Item Type: Article
Uncontrolled Keywords: dietary interventions; protein enriched; insulin sensitivity; glycemic control
Subjects: Engineering > MIT Manipal > Biomedical
Depositing User: MIT Library
Date Deposited: 08 Feb 2017 10:01
Last Modified: 08 Feb 2017 10:01
URI: http://eprints.manipal.edu/id/eprint/148258

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