Clinicopathological Profile of Patients with Lymphadenopathy

Shivamurthy, Archana and Suppiah, Alagappan and Mahandran, Kishor Kumar and Eunice, Yong (2016) Clinicopathological Profile of Patients with Lymphadenopathy. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7 (6). pp. 100-106. ISSN 0975-8585

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Lymphadenopathy is a common clinical finding and may be due to a variety of causes ranging from inflammatory lesions to malignancies. Correlation between clinical findings, fine needle aspiration cytology and biopsy are essential in arriving at a definitive diagnosis. Clinical features, cytology and histopathology findings of 100 patients presenting with lymphadenopathy were obtained retrospectively from the medical records department. All clinical features and histopathological features were identified and results were tabulated. Fine needle aspiration cytology findings (FNAC) were noted where ever available. The age group ranged between 16-79yrs with a mean age of 47.5yrs and a male predominance. Fever was noted in 28%, associated pain in 44% and cough in 33% of cases. Weight loss, vomiting and fatigue were noted in a few cases. Majority of the cases presented with cervical lymphadenopathy followed by the axillary and inguinal node involvement. All findings of cytology correlated with the histopathological diagnosis in 36 cases where FNAC was available. Among the 100 cases with histopathological biopsy, metastatic carcinoma was the predominant cause of lymphadenopathy. Patients with lymphadenopathy can present with various symptom like fever, cough, fatigue and weight loss. Metastatic carcinoma is the predominant cause of lymphadenopathy in our study. Correlating clinical features with the cytology and histopathological findings would help in understanding the causes of lymphadenopathy.

Item Type: Article
Uncontrolled Keywords: Lymphadenopathy; Tuberculosis; Lymphoma
Subjects: Medicine > MMMC Manipal > Pathology
Depositing User: KMC Library
Date Deposited: 10 Feb 2017 14:31
Last Modified: 10 Feb 2017 14:31

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