A Fortuitous Turn of Evidence in an Elderly Female – A Case of Pulmonary Fusariosis

*, Saraswathy Sreeram and Lobo, Flora Dorothy and Acharya, Vishak K. and Saralaya, Vishwas (2017) A Fortuitous Turn of Evidence in an Elderly Female – A Case of Pulmonary Fusariosis. Journal of Clinical and Diagnostic Research, 11 (2). ED04-ED05. ISSN 0973-709X

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Pulmonary mycosis is seen infrequently in our country. It is more common in the immunocompromised. The infections caused by less known species like Fusarium have been found to be increasing in incidence in other parts of the world. We hereby report its occurrence in a 79-year-old, non-immunocompromised female who presented with pyrexia of unknown origin. Her ALP and LDH levels were raised. CT scan showed interstitial thickening in subpleural aspect of lungs and multiple enlarged lymph nodes in mediastinum. Liver showed multiple hypodense lesions. Metastasis was suspected for which FNAC of liver was done which showed foci of regenerative hepatocytes with desmoplastic stromal tissue fragments and negative for tumour. Her AFP was normal. The bronchial tree cytology showed endobronchial cells, dust-laden macrophages and chronic inflammatory cells along with fungi on Pap smear studies. This was confirmed by culture that grew Fusarium species. after one week of incubation. The acutely branching septate hyphae of Fusarium species are identical to those of Aspergillus species. In a patient who has a disseminated infection with a septate fungus, growth in culture is important to identify the specific organism and subsequently treatment with appropriate antifungals. In cases like ours, where the infection simulates malignancy, it is even more important to make the correct diagnosis to give the appropriate treatment.

Item Type: Article
Uncontrolled Keywords: Cytology, Filamentous fungi, Fusarium, Immunocompetent, Lung cancer
Subjects: Medicine > KMC Mangalore > Microbiology
Medicine > KMC Mangalore > Pathology
Medicine > KMC Mangalore > Pulmonary Medicine
Depositing User: KMCMLR User
Date Deposited: 18 Feb 2017 11:35
Last Modified: 18 Feb 2017 11:35
URI: http://eprints.manipal.edu/id/eprint/148331

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