Can strain elastography is used as an adjunct to conventional imaging in differentiating benign and malignant breast lesions?

Bajjuri, Vikram Kumar and Sripathi, Smiti and Rajagopal, KV (2016) Can strain elastography is used as an adjunct to conventional imaging in differentiating benign and malignant breast lesions? Indian Journal of Applied Research, 6 (4). pp. 91-95. ISSN 2249-555X

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Abstract

Aims and Objectives: • To compare mammography, ultrasound and strain elastography in differentiating solid breast lesions into benign and malignant lesions. • To assess the sensitivity, specificity, Positive predicative value(PPV), Negative predictive value(NPV) and Accuracy of ultrasound and combined ultrasound and strain elastography in BIRADS category III and IV lesions. Study design: Mammography, ultrasound and strain elastography were done in 69 lesions(66 patients). Results: The mean strain index value on elastography was 2.49 ± 1.49 for benign and 6.45 ± 2.68 for malignant lesions with a sensitivity and specificity of 89.8% and 75% respectively. The sensitivity, specificity, accuracy, PPV and NPV for ultrasound were 94%, 73.68%, 88.4%, 90.38%, 82.35% which improved on adding strain elastography to 96%, 84.21%,92.75%,94.11%, 88.88 % respectively. Sensitivity, Specificity, Accuracy, PPV and NPV were 80%,85.71%,80%,85.71% and 83.33 respectively for combined ultrasound and elastography in category III and IV lesions. Conclusion: • Strain index cut off value of 3.37 enabled the best distinction between benign and malignant lesions on elastography. • Adding strain elastography to ultrasound improved sensitivity, specificity, PPV, NPV and Accuracy when compared to ultrasound or Mammography used alone.

Item Type: Article
Uncontrolled Keywords: Breast; ultrasound; mammography; strain index and elastography.
Subjects: Medicine > KMC Manipal > Radiology
Depositing User: KMC Library
Date Deposited: 25 Mar 2017 04:05
Last Modified: 25 Mar 2017 04:05
URI: http://eprints.manipal.edu/id/eprint/148560

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