Bortezomib Induced Subconjunctival Hemorrhage

Patil, Navin and Balaji, O and Udupa, Karthik S and Rao, Karthik N (2017) Bortezomib Induced Subconjunctival Hemorrhage. Asian Journal of Pharmaceutical and Clinical Research, 10 (4). pp. 10-11. ISSN 0974-2441

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Abstract

Many drugs are used in the treatment of multiple myeloma but thalidomide, lenalidomide, bortezomib, and dexamethasone and their combination remain the main stay of treatment. The molecular formula of bortezomib is C19H25BN4O4 and its chemical name is (3-methyl-1-(3-phenyl-2-pyrazin-2- ylcarbonylamino-propanoyl) amino-butyl) boronic acid. Mechanisms by which it acts is usually by 26 SProteasome inhibition leading to degradation of anti-apoptotic proteins. Bortezomib is known to cause many side effects. Hence, we report a rare case of bortezomib-induced subconjunctival hemorrhage in our tertiary care hospital.

Item Type: Article
Uncontrolled Keywords: Bortezomib; Adverse effect; Proteaosome inhibition; Subconjunctival hemorrhage
Subjects: Medicine > KMC Manipal > Medicine
Medicine > KMC Manipal > Medical Oncology
Medicine > KMC Manipal > Pharmacology
Depositing User: KMC Library
Date Deposited: 08 Apr 2017 09:59
Last Modified: 08 Apr 2017 09:59
URI: http://eprints.manipal.edu/id/eprint/148675

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