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Effect of oil extract of jasminum grandiflorum leaves on wound healing activity in albino rats

Almeida, Prathibha MD and Mandal, Tatiyana and Bairy, KL and Adiga, Shripathi H (2017) Effect of oil extract of jasminum grandiflorum leaves on wound healing activity in albino rats. Advanced Science Letters, 23 (3). pp. 1957-1959. ISSN 1936-6612

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Abstract

Medicinal plants are being used for the treatment of diseases for several decades. Jasminum grandiflorum plant is used in ayurveda for wound healing. The study was undertaken to investigate the effect of oil extract of Jasminum grandiflorum leaves on various wound models in albino rats. Study groups were as follows, Group 1: control (distilled water), Group 2: vehicle control (coconut oil), Group 3: standard (aloe vera), and Group 4: test (oil extract of Jasminum grandiflorum fresh leaves). In excision wound model, a 500 mm sized skin was excised with the help of sharp scissors from the back of the anesthetized rat. Burn wound model was induced by using hot molten wax to make a wound of 500 mm . Percentage of wound contraction and duration required for epithelisation was observed. Test groups showed significant decrease in periods of epithelialization when compared to control and vehicle control groups in excision wound (p < 0.05) and burn wound (p < 0.001) models. Wound contraction rate was also increased significantly in test groups (p < 0.001) in both the models. Oil extract of Jasminum grandiflorum leaves has shown wound healing effects in burn wounds and excision wounds.

Item Type: Article
Uncontrolled Keywords: Burn wound; coconut oil; excision wound; Jasminum grandiflorum oil extract; wistar rats.
Subjects: Medicine > KMC Manipal > Ayurveda
Medicine > MMMC Manipal > Pharmacology
Medicine > MMMC Manipal > Physiology
Medicine > KMC Manipal > Pharmacology
Depositing User: KMC Library
Date Deposited: 02 May 2017 10:59
Last Modified: 02 May 2017 10:59
URI: http://eprints.manipal.edu/id/eprint/148777

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