Advanced diagnostic techniques in autoimmune bullous diseases

Jindal, Anuradha and Rao, Raghavendra (2017) Advanced diagnostic techniques in autoimmune bullous diseases. Indian Journal of Dermatology, 62 (3). pp. 268-278. ISSN 0019-5154

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Autoimmune blistering diseases are diverse group of conditions characterized by blisters in the skin with or without mucosal lesions. There may be great degree of clinical and histopathological overlap; hence, advanced immunological tests may be necessary for more precise diagnosis of these conditions. Direct immunofluorescence microscopy is the gold standard tests to demonstrate the tissue-bound antibodies and should be done in all cases. Magnitude of antibody level in patient' serum can be assessed by indirect immunofluorescence and enzyme linked immunosorbent assay. In this article we have reviewed the various techniques that are available in the diagnosis of autoimmune blistering diseases.

Item Type: Article
Uncontrolled Keywords: Autoimmune bullous diseases; direct immunofluorescence; ELISA.
Subjects: Medicine > KMC Manipal > Dermatology
Depositing User: KMC Library
Date Deposited: 22 May 2017 03:41
Last Modified: 22 May 2017 03:41

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