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Epigenetics and Human Diseases

Kotambail, Ananthapadmanabha and Bhat, Smitha and Jayaprakash, Chinchu and Fernandes, Rayzel Candida and Varghese, Vinay Koshy and Satyamoorthy, K (2017) Epigenetics and Human Diseases. In: Human Genomics and Applications. Narendra Publishing House, Delhi, India, pp. 73-100.

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Abstract

Epigenetics is the study of heritable but potentially reversible changes that regulate expression  of the gene (phenotype) and are not due to any direct change in the DNA sequence compositionper se. The epigenetic mechanism is an essential process for normal development and various machineries are involved to carry out this process. The role of epigenetics has been implicated in a number  of human diseases and disorders. Recent evidences suggest that environmental factors significantly  alter the expression of the genes through epigenetic modifications and may influence the process of disease development. Here, we present a concise view where we highlight the current topic of  our interest in the field  of epigenetics covering  vast areas of epigenetic research, directly or  indirectly in relation to the role of its mechanisms and etiology of human diseases.

Item Type: Book Section
Subjects: Life Sciences > MLSC Manipal
Depositing User: KMC Library
Date Deposited: 10 Jun 2017 03:53
Last Modified: 10 Jun 2017 03:53
URI: http://eprints.manipal.edu/id/eprint/149030

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