Pawlak, Zenon and Yusuf, Kehinde Q. and Pai, Raghuvir B and Urbaniak, Wieslaw (2017) Repulsive surfaces and lamellar lubrication of synovial joints. Archives of Biochemistry and Biophysics, 623 (624). pp. 42-48. ISSN 00039861

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Abstract

Surface-active phospholipid (SAPL) secreted in the synovial joint plays an important role in cartilage integrity. In healthy joints, phospholipid multibilayers coat the cartilage surface, providing boundary lamellar-repulsive hydration lubrication. Current mechanism for lubrication of synovial joints, as well as the physical and chemical nature of the cartilage surface is discussed. Friction between phospholipid (PL) bilayers attached to cartilage surfaces is considered including a discussion on the recent observation of an extreme friction reduction as a consequence of a less charged hydrophilic cartilage surface. It is proposed that the highly efficient lubrication occurring in natural joints arises from the presence of negatively charged cartilage surfaces. The lamellar-repulsive mechanisms for the reduction of friction is supported by phospholipid lamellar phases and charged macromolecules residing between contacting cartilage surfaces at pH ~7.4

Item Type:	Article
Uncontrolled Keywords:	Synovial joint, Wettability,Lamellar repulsive lubrication,Hydration repulsion,Fixed charge density
Subjects:	Engineering > MIT Manipal > Mechanical and Manufacturing
Depositing User:	MIT Library
Date Deposited:	23 Jun 2017 08:47
Last Modified:	23 Jun 2017 08:47
URI:	http://eprints.manipal.edu/id/eprint/149141

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