A review on the application of nanotechnology in the treatment of hypertension

Bhaskaran, Navya and Vamshi, Krishna T (2016) A review on the application of nanotechnology in the treatment of hypertension. Journal of Global Pharma Technology, 7 (9). pp. 25-31. ISSN 0975 -8542

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Abstract

Hypertension or elevated blood pressure is a common chronic disease. It is associated with severe symptoms like aneurysms, chronic kidney disease, amnesia, improper speech, blindness, peripheral artery disease, brain stroke, heart attack etc. Pathophysiology for hypertension involves the role of autonomous nervous system, cardiac output and renin-angiotensin aldosterone system. This review article mainly deals with the application of nanotechnology and nanoparticulate drug delivery systems in the formulation of various antihypertensive drugs for the treatment of hypertension. Application of various nanoparticulate drug delivery systems like solid lipid nanoparticles, polymeric nanoparticles, nanosuspensions and self-nanoemulsifying drug delivery systems for antihypertensive drugs have been reviewed and discussed in this article which indicates that the bioavailability of various poorly soluble and permeable antihypertensive drugs can be improved using these nano carriers.

Item Type: Article
Uncontrolled Keywords: Hypertension; nanotechnology; nanoparticles.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Library
Date Deposited: 12 Jul 2017 03:55
Last Modified: 12 Jul 2017 03:55
URI: http://eprints.manipal.edu/id/eprint/149326

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