Pharmacognostical standardisation and cytotoxicity screening of bridelia retusa spreng

Xavier, Seena Kanniparambil and Praveen, KS and Devkar, Raviraj Ananad and Shreedhara, CS and Setty, Manjunath M (2017) Pharmacognostical standardisation and cytotoxicity screening of bridelia retusa spreng. Advanced Science Letters, 23 (3). pp. 1773-1776. ISSN 1936-6612

[img] PDF
RMS - 00002921.pdf - Published Version
Restricted to Registered users only

Download (5MB) | Request a copy

Abstract

Bridelia retusa is an indigenous medicinal plants belonging to family Euphorbiaceae and are used in the treatment of various disorders such as inflammation, kidney stones, urinary disorders, diarrhoea and dysentery. The stem bark of Bridelia retusa was subjected for macro and microscopical analysis, various physico chemical standardisation parameters and phytochemical studies according to Indian Pharmacopoeia. Total phenolic and flavonoid content were estimated using standard procedures. Cytotoxicity screening of methanol extract of Bridelia retusa was performed in Vero cells by sulforhodamine assay. The present study provides standardisation parameters for Bridelia retusa which will aid in the proper identification and authentication of the plant. Further, results of cytotoxicity screening revealed that plant exhibits no toxicity even at higher concentration and IC50 was found to be 430.6 μg/ml.

Item Type: Article
Uncontrolled Keywords: Bridelia retusa; pytotoxicity; pharmacognostical ptandardisation; physicochemical parameters.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Biotechnology
Pharmacy > MCOPS Manipal > Pharmacognosy
Depositing User: KMC Library
Date Deposited: 21 Jul 2017 06:47
Last Modified: 21 Jul 2017 06:47
URI: http://eprints.manipal.edu/id/eprint/149392

Actions (login required)

View Item View Item