Protein kinases as drug targets in human and animal diseases

Kini, Suvarna G and Garg, Vikas and Prasanna, Sharada and Rajappan, Revathi and Mubeen, Muhammad (2017) Protein kinases as drug targets in human and animal diseases. Current Enzyme Inhibition, 13 (2). pp. 99-106. ISSN 1573-4080

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Almost thirty percent of the protein targets currently under exploration and study constitute the protein kinases which have always attracted the pharmaceutical companies as they are easy targets for drug development. Although the kinases will remain major focus of oncology for many years to come in the development of anticancer drugs, the number of kinase inhibitors as therapeutic targets for the treatment of several other diseases which are undergoing clinical trials are exponentially increasing. In this review, we discuss very briefly the different types of protein kinases that have been used as targets for developing drugs for cancer, inflammation, autoimmune disease, heart disease and animal diseases.

Item Type: Article
Uncontrolled Keywords: Cancer; inflammatory and autoimmune diseases; kinases; protein kinases.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Depositing User: KMC Library
Date Deposited: 31 Jul 2017 04:10
Last Modified: 31 Jul 2017 04:10

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