Fecal Carriage of Extended‑spectrum Beta‑lactamase‑producing Enterobacteriaceae in Intensive Care Unit Patients

Shenoy, Shalini and *, Kavya Ramamurthy and Bhat, Sevitha (2017) Fecal Carriage of Extended‑spectrum Beta‑lactamase‑producing Enterobacteriaceae in Intensive Care Unit Patients. Indian Journal of Critical Care Medicine, 21 (8). pp. 525-527. ISSN 09725229

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Abstract

Background and Aims: Increasing and indiscriminate use of antibiotics has led the bacteria to develop resistance to most of the antibiotics. Beta‑lactamase production is the mechanism of resistance to beta‑lactams. Extended‑spectrum beta‑lactamases (ESBLs) have been found in the members of Enterobacteriaceae such as Escherichia coli and Klebsiella spp. which are the common health‑care‑associated pathogens. The aim was to study the rate of fecal carriage of ESBL‑producing Enterobacteriaceae in patients admitted to the Intensive Care Unit (ICU) of tertiary care hospital and follow them subsequently for the development of infections. Materials and Methods: A hospital‑based descriptive study was conducted in the department of microbiology of a tertiary care hospital for a period of 2 months from June 2016 to August 2016. Rectal swabs were collected from the patients admitted to the ICU after a period of 48 h. The swab was inoculated onto a special selective media (ChromID ESBL media). The results were noted according to the color of the colony produced. These patients are followed for the development of infection and the ESBL‑producing organisms. Results: A total of 60 rectal swabs were cultured, 39 (65%) showed a positive result. Out of which, 22 (56%) were ESBL‑producing E. coli and 17 (43%) Klebsiella spp. Twenty‑three (38%) of the total patients screened were infected with ESBL‑producing organisms. Conclusion: The study revealed high rates of carriage of ESBL producers in patients admitted to the ICU.

Item Type: Article
Uncontrolled Keywords: Escherichia coli, extended‑spectrum beta‑lactamase, fecal carriage, Intensive Care Unit
Subjects: Medicine > KMC Mangalore > Microbiology
Depositing User: KMCMLR User
Date Deposited: 17 Aug 2017 04:50
Last Modified: 17 Aug 2017 04:50
URI: http://eprints.manipal.edu/id/eprint/149537

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