Unresectable squamous cell carcinoma of upper trachea with long-term survival after concurrent chemoradiotherapy

Yathiraj, Prahlad H and Ail, Sandeep and Singh, Anshul and Vidyasagar, MS (2017) Unresectable squamous cell carcinoma of upper trachea with long-term survival after concurrent chemoradiotherapy. BMJ Case Report. pp. 1-4. ISSN 1757-790X

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Abstract

Upper tracheal malignancies are rare, and long-term survival is even rarer, especially among the unresectable malignancies. A 66-year-old chronic smoker was diagnosed as a locally advanced, non-metastatic squamous cell carcinoma of the upper trachea. Being unresectable, he was treated with six cycles of concurrent weekly cisplatin and three-dimensional conformal radiotherapy to a dose of 60 Gy in 30 fractions over 6 weeks. Follow-up imaging at 6 and 12 months revealed no disease. Our patient is presently 36 months post-treatment and is disease free without tracheal necrosis, fistula or radiation pneumonitis but developed hypothyroidism and is presently euthyroid. Concurrent chemoradiotherapy appears safe up to 3 years at least without any necrosis and is effective in controlling local disease. Meticulous planning obviates the need for higher technology like motion management techniques or intensity-modulated radiotherapy.

Item Type: Article
Subjects: Medicine > KMC Manipal > Radiotherapy and Oncology
Depositing User: KMC Library
Date Deposited: 24 Aug 2017 10:58
Last Modified: 24 Aug 2017 10:58
URI: http://eprints.manipal.edu/id/eprint/149576

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