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Temozolomide and its stability—A critical factor

Attari, Zenab and Rao, Mallikarjuna C and Kumar, Lalit and Koteshwara, KB (2017) Temozolomide and its stability—A critical factor. Advanced Science Letters, 23 (3). pp. 1841-1845. ISSN 1936-6612

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Abstract

Temozolomide is an alkylating agent, used in the treatment of glioblastoma multiforme. The characterization of the pure drug and its expired batch was carried out to evaluate the changes occurred due to degradation of the drug. FT-IR spectrocscopy, DSC analysis and drug content estimation were carried out. The observations indicated the changes in the drug peak and content after expiry period.

Item Type: Article
Uncontrolled Keywords: Temozolomide; stability; FT-IR; DSC termograms; drug content.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Library
Date Deposited: 31 Aug 2017 09:19
Last Modified: 31 Aug 2017 09:19
URI: http://eprints.manipal.edu/id/eprint/149614

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