Morphometric and histological analysis of 'spondylosis deformans' of thoracic region in south-indian cadaveric spines

Kumar, Naveen and Aithal, Ashwini P and Swamy, Ravindra S and Bishnu, Arijit and Nayak, Satheesha B and Rao, Mohandas KG (2017) Morphometric and histological analysis of 'spondylosis deformans' of thoracic region in south-indian cadaveric spines. Journal of Krishna Institute of Medical Sciences University, 6 (3). pp. 94-102. ISSN 2231-4261

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Abstract

Background: Osteophyte is a bony outgrowth in the vertebral column. Its high prevalence and clinical importance prompted us to conduct this study of thoracic osteophytes. Aim and Objectives: Morphometric and histological study of thoracic osteophytes in the cadaveric vertebral column to understand their development, frequency of occurrence and distribution. Material and Methods: Frequency of occurrence of osteophytes was studied in 50 cadavers of Indian origin over a period of five years. The thoracic part of the vertebral columns were dissected and examined. The vertebral levels of osteophytes, their exact distribution, and morphometric measurements were recorded. A small piece of the osteophyte was removed, processed and stained with Haemetoxylin & Eosin [H & E] stains for histopathological examination. Results: Osteophytes were present in 7 specimens (14%). They were predominantly found on the right side of the lower thoracic vertebral bodies. H & E stained sections of the osteophytes showed features resembling a cancellous bone which strongly indicate that the osteophytes are in development stage, and they develop by the process of endochondral ossification. Conclusion: We found a high incidence of thoracic osteophytes in our study, which mandates further studies in this regard.

Item Type: Article
Uncontrolled Keywords: Osteophytes; Bone Spurs; Thoracic Vertebra; Cadaveric Spine.
Subjects: Medicine > MMMC Manipal > Anatomy
Medicine > MMMC Manipal > Pathology
Depositing User: KMC Library
Date Deposited: 11 Sep 2017 11:11
Last Modified: 11 Sep 2017 11:11
URI: http://eprints.manipal.edu/id/eprint/149672

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