An update on solubility enhancement methods for BCS Class -II drugs

Naaz, Shaik and Vamshi, Krishna T (2017) An update on solubility enhancement methods for BCS Class -II drugs. Journal of Global Pharma Technology, 9 (9). pp. 48-57. ISSN 0975 -8542

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To attain the anticipated concentration of a drug in the systemic circulation in order to exhibit the pharmacologic response, solubility of the drug plays a critical role. Key research problems faced during formulation development of various drugs owe to their low aqueous solubility. About 40% of NCEs are unsuccessful in reaching their therapeutic range mainly due to their solubility issues. In this context, this review article details various solubility enhancement techniques and their application mainly to address this poor solubility of various BCS class-II drugs.

Item Type: Article
Uncontrolled Keywords: Solubility Enhancement Methods; BCS Class-II drugs.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Library
Date Deposited: 18 Sep 2017 10:56
Last Modified: 18 Sep 2017 10:56

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