Structural and elemental characterization of traditional Indian Siddha formulation: Thalagak karuppu

Kannan, N and Balaji, S and Kumar, Anil N V (2017) Structural and elemental characterization of traditional Indian Siddha formulation: Thalagak karuppu. Journal of Ayurveda & Integrative Medicine, 8 (3). pp. 184-189. ISSN 0975-9476

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Background: The traditional Indian medicine ‘Siddha’ uses metals, metalloids and minerals including toxic ones with no proven toxicity. Thalagak karuppu (TK) is remarkably stable over a century and used for treating Suram (Fever), Kaasam (Cough), Elai (Tuberculosis) and Eraippu Erumal (Bronchial Asthma). Objective: The present study addresses elemental and morphological characterization of therapeutic Siddha formulation: Thalagak karuppu (TK). Materials and methods: TK was purchased from the Indian Medical Practitioners Co-operative Pharmacy and Stores (IMCOPS) Ltd, Chennai, Tamilnadu, India. The physicochemical properties were evaluated using UVevisible spectrophotometer, Fourier Transform Infrared Spectrometer (FTIR), Scanning Electron Microscope (SEM) with Energy Dispersive X-ray analysis (EDX), Zeta sizer and X-ray diffractometer (XRD). Results: The mixed nature of arsenic was analyzed using UVevisible spectroscopy. The fingerprint region for arsenic derivatives was inferred from IR spectroscopy and X-ray diffraction patterns. The shape and size heterogeneity in the anisotropic mixture was observed in SEM images and the polydispersity was analyzed by Zeta sizer. Conclusions: The structural, elemental and morphological analyses suggests that the arsenic may predominantly exist either as orpiment (As2S2) or realgar (As2S4) form. The possibility is less for the toxic arsenolite. Hence, the formulation may be considered safe. © 2016 Transdisciplinary University, Bangalore and World Ayurveda Foundation. Publishing Services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license

Item Type: Article
Uncontrolled Keywords: Thalagak karuppu;Siddha;Arsenic;Orpiment;Realgar
Subjects: Engineering > MIT Manipal > Biotechnology
Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 21 Sep 2017 10:53
Last Modified: 21 Sep 2017 10:53

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