Bisht, Madhoolika and Kumar, Anil N V and Balaji, S (2017) In vitro analysis of 4-methylumbelliferone as a sole carbon source for Lactobacillus helveticus 2126. Letters in Applied Microbiology, 65 (3). pp. 249-255. ISSN ISSN 0266-8254
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Abstract
In the recent years, 4-methylumbelliferone (4-MU) has been gaining importance, both as an anti-cancer agent and as a dietary supplement. The aim of this study was to determine the effectiveness of 4-MU as a carbon source for potential probiotic bacteria Lactobacillus helveticus 2126. For this purpose, a series of plate assays and infrared spectroscopy (FTIR) were used for 4-MU before and after the treatment with L. helveticus 2126. The plate assays indicated an initial inhibition followed by utilization of 4-MU that stimulated bacterial growth. A significant shift was observed in the FTIR peaks, which also have suggested possible extracellular activity of the bacteria for 4-MU utilization.
Item Type: | Article |
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Uncontrolled Keywords: | 4–methylumbelliferone, carbon source, coumarin, Lactobacillus helveticus, prebiotic |
Subjects: | Engineering > MIT Manipal > Biotechnology Engineering > MIT Manipal > Chemistry |
Depositing User: | MIT Library |
Date Deposited: | 21 Sep 2017 10:51 |
Last Modified: | 21 Sep 2017 10:51 |
URI: | http://eprints.manipal.edu/id/eprint/149722 |
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