Antiurolithiatic Activity of Aqueous Extract of Moringa Oleifera (Lam.) Pod in Rats

Jameel Fahad, Jameel Fahad and *, Vijayalakshmi and *, M. C. Satish Kumar and *, Sanjeeva and *, Prabhath Kodancha and Benegal , Adarsh and *, A. L. Udupa and *, U. P. Rathnakar (2010) Antiurolithiatic Activity of Aqueous Extract of Moringa Oleifera (Lam.) Pod in Rats. Pharmacologyonline, 3. pp. 716-721.

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Abstract

In the present study, aqueous extract of Moringa oleifera was evaluated for its antiurolithiatic potential in albino rats of Wistar strain. The vesical calculi were produced by zinc disc insertion into the urinary bladder of rats supplemented with 1%ethylene glycol in drinking water. The drug / extract was administered orally daily in two doses (400mg and 800mg/kg) for four to eight weeks in different groups of animals [Prophylactic and Curative].The reduction in weight of the vesical calculi was used as criteria for assessing the prophylactic or curative antiurolithiatic effect of the pods of this plant. In both the groups the administration of the aqueous extract of Moringa oleifera pods [AEMO] has resulted in significant reduction in the weight of calculi as compared to the control group. It can be concluded that pods of Moringa oleifera has antiurolithiatic activity.

Item Type: Article
Uncontrolled Keywords: Moringa oleifera, antiurolithiatic activity, zinc disc.
Subjects: Medicine > KMC Mangalore > Pharmacology
Depositing User: KMCMLR User
Date Deposited: 13 Oct 2011 11:13
Last Modified: 14 Oct 2011 05:53
URI: http://eprints.manipal.edu/id/eprint/1500

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