Congenital scoliosis; An anomalous association with endosulfan

Jayakrishnan, KN and Mohanty, SP (2017) Congenital scoliosis; An anomalous association with endosulfan. BMJ Case Report, 102 (12). pp. 1-19. ISSN 1757-790X

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Endosulfan is an organochlorine pesticide that is used extensively across the world to kill insects. Incidence of acute and chronic toxicity with endosulfan poisoning has been reported, and nearly 80 countries have banned its use. However, it is still being used in many low-income/middle-income countries. One of the most severe tragedies because of endosulfan poisoning has taken place in the Indian state of Kerala due to persistent aerial spraying of endosulfan. Even though there are reports of skeletal and other congenital abnormalities in humans and experimental animals following exposure to endosulfan, very few have been documented. We report two cases of congenital scoliosis in siblings living in a community affected by high levels of endosulfan in the environment. High index of suspicion is essential during the screening of school children exposed to endosulfan. Congenital scoliosis is a progressive deformity that leads to severe disability, unless detected and corrected at an early stage.

Item Type: Article
Uncontrolled Keywords: Poisoning; emergency medicine, carcinogenesis; oncology, screening (oncology); oncology, congenital disorders; paediatrics, disability; rehabilitation medicine.
Subjects: Medicine > KMC Manipal > Orthopaedics
Depositing User: KMC Library
Date Deposited: 20 Dec 2017 08:53
Last Modified: 20 Dec 2017 08:53

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