Manipal diabetes coronary artery severity score

*, Mukund P Srinivasan and Kamath, Padmanabh K and Bhat, Narayan M and Pai, Narasimha D and Bhat, Rajesh U and Manjrekar, Poornima and *, Chakrapani M (2016) Manipal diabetes coronary artery severity score. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 11 (1). SS33-SS37. ISSN 18714021

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Abstract

Aims: To develop a risk score, for identifying severe and complex CAD in patients with type 2 diabetes mellitus. Methods: In this cross sectional study, 179 patients with type 2 diabetes mellitus undergoing coronary angiogram for the evaluation of suspected coronary artery disease (CAD) were recruited at a tertiary-care hospital. Patients were divided into developmental (n = 124) and validation (n = 55) cohorts. Biochemical and anthropometric parameters were analysed. Predictors of severe and complex CAD (SYNTAX Score > 22) were identified by multiple logistic regression analysis. Results: Insulin resistance > 3.4 (OR: 21.26, 95% CI: 5.71–79.09), duration of diabetes > 5 years (OR: 13.50, 95% CI: 3.13–58.25), total cholesterol/HDL-C ratio > 5 (OR: 2.75, 95% CI: 0.66–11.55) and waist circumference > 96 cm (OR: 5.08, 95% CI: 1.27–20.42) were independent predictors of severe and complex CAD, and Manipal Diabetes Coronary Artery Severity Score was developed. Conclusions: The prediction of severe and complex CAD was achieved with this simple score, and thus enabling effective identification of patients beforehand, who are not likely to be suitable for angioplasty.

Item Type: Article
Uncontrolled Keywords: Insulin resistance Type 2 diabetes mellitus Coronary artery disease SYNTAX score
Subjects: Medicine > KMC Mangalore > Cardiology
Medicine > KMC Mangalore > Biochemistry
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 22 Dec 2017 05:47
Last Modified: 22 Dec 2017 05:47
URI: http://eprints.manipal.edu/id/eprint/150338

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