Circulating Genotypes of Dengue-1 Virus in South West India, 2014–2015

Shetty, Pooja and Sasidharanpillai, Sabeena and Bhaskar, Revti and Ramachandran, Sanjay and Aithal, Anjali and Kumar, Rajendra and Aswathyraj, Sushama and Dsouza, Giselle and Hindol, Maity and Arunkumar, G Circulating Genotypes of Dengue-1 Virus in South West India, 2014–2015. Japanese Journal of Infectious Diseases, 70. pp. 663-665.

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Abstract

subtropical regions having the highest risk of dengue virus infections. The clinical symptoms often range from mild fever to fever with hemorrhagic manifestations and shock. Since 2010, India has been witnessing a marked increase in the number of dengue virus serotype 1 (DENV-1) infections, apart from those of serotypes 2 (DENV-2) and 3 (DENV-3). The present study was undertaken to understand the circulating genotypes of DENV-1 in South West India, by sequencing the envelope gene of DENV- 1 samples representative of the 2014–2015 time period. The extracted RNAs from dengue NS1 antigen ELISA-positive samples, archived at the APEX Referral Laboratory for Arboviruses (National Vector Borne Disease Control Programme, Manipal Centre for Virus Research), were used for the study. The currently circulating genotypes of DENV-1 identified from the study area belong to genotypes V and I.Multicentric laboratory-based studies analyzing the envelope gene of all dengue serotypes are required from endemic countries like India

Item Type: Article
Subjects: Departments at MU > Manipal Centre for Virus Research
Depositing User: KMC Library
Date Deposited: 02 Jan 2018 10:13
Last Modified: 02 Jan 2018 10:13
URI: http://eprints.manipal.edu/id/eprint/150418

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