Estimation of Salivary Cortisol among Subjects Undergoing Dental Extraction

Gadicherla, Srikanth and Shenoy, Revathi P and Patel, Bhavik and Ray, Meenakshi and Naik, Brijesh and Pentapati, Kalyana Chakravarthy (2018) Estimation of Salivary Cortisol among Subjects Undergoing Dental Extraction. Journal of Clinical and Experimental Dentistry, 10 (2). pp. 116-119. ISSN 1989-5488

[img] PDF
3958 DisplayPdf.pdf - Published Version
Restricted to Registered users only

Download (278kB) | Request a copy


Background: Dental procedures can be stressful and studies have shown that salivary cortisol is elevated during such procedures. Our study aimed to evaluate saliva cortisol levels among the subjects who underwent dental extractions and to compare it with that of the controls. The secondary objective of the study was to evaluate any correlation between salivary cortisol and hemodynamic parameters.Material and Methods: We conducted this clinical study among subjects, who were indicated for dental extraction.Saliva samples from the subjects in the study group were collected before and after (10 mins) the dental extraction.Hemodynamic parameters like heart rate, systolic (SBP) and diastolic blood pressure (DBP) and oxygen saturation (Sp O2) were measured 10 minutes prior to the dental extraction and after completion of the extraction by a single trained examiner. Salivary cortisol was estimated by solid phase enzyme-linked immunosorbent assay (ELISA).Results: A total of 31 subjects in the study group and 24 subjects in control group have participated in this study.The mean salivary cortisol concentration was significantly higher after extraction (27.94±7.94) than before extraction (24.67±8.31) in the study group (P<0.001). No significant correlations were seen between salivary cortisol concentration and hemodynamic parameters except for diastolic blood pressure after extraction. Conclusions: Dental extractions and local anaesthetic procedures can induce stress in subjects. Dental care providers should try to minimise the subject’s anxiety and stress to the maximum extent.

Item Type: Article
Uncontrolled Keywords: Cortisol; Dental; Extraction; Saliva; Stress
Subjects: Medicine > KMC Manipal > Biochemistry
Dentistry > MCODS Manipal > Preventive and Community Dentistry
Dentistry > MCODS Manipal > Oral and Maxillofacial Surgery
Depositing User: KMC Library
Date Deposited: 13 Feb 2018 06:39
Last Modified: 13 Feb 2018 06:39

Actions (login required)

View Item View Item