Giant‑cell fibroma: Understanding the Nature of the Melanin‑laden Cells

Kulkarni, Spoorti and Chandrashekar, Chetana and Kudva, Ranjani and Radhakrishnan, Raghu (2017) Giant‑cell fibroma: Understanding the Nature of the Melanin‑laden Cells. Journal of Oral and Maxillofacial Pathology, 21 (3). pp. 429-433. ISSN 0973-029X

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Abstract

Giant‑cell fibroma is a localized, benign fibrous mucosal mass, which clinically mimics any other fibroepithelial growth, and its distinction from other lesions is on the basis of its peculiar histopathology. A case of giant‑cell fibroma with stroma strewn with brown pigment‑laden cells is presented herewith. Immunohistochemical staining aided with histochemical reaction to understand the origin of these cells was carried out. Various mechanisms that explain the presence of melanin granules in reactive lesions of giant‑cell fibroma is discussed in the present report.

Item Type: Article
Uncontrolled Keywords: Giant cells; Immunohistochemistry; Melanin granules; Special stains
Subjects: Dentistry > MCODS Manipal > Oral Pathology and Microbiology
Medicine > KMC Manipal > Pathology
Depositing User: KMC Library
Date Deposited: 15 Feb 2018 03:46
Last Modified: 15 Feb 2018 03:46
URI: http://eprints.manipal.edu/id/eprint/150598

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