Evaluation of Instant Desensitization after a Single Topical Application over 30 days: A Randomized Trial

Samuel, SR and Khatri, SG and Acharya, Shashidhar (2015) Evaluation of Instant Desensitization after a Single Topical Application over 30 days: A Randomized Trial. Australian Dental Journal, 60. pp. 336-342.

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Abstract

Background: The aim of this study was to evaluate the efficacy of ProArginTM (8% arginine), Gluma� and NovaMin (5% calcium phosphosilicate) in relieving dentinal hypersensitivity immediately and over 30 days following a single topical application. Methods: A three-cell, parallel group randomized trial was conducted among 56 patients exhibiting dentinal hypersensitivity with tooth as the unit of study. ProArginTM paste, Gluma� Desensitizer and NovaMin� paste were applied on randomly assigned teeth in each participant. Three stimuli were tested: tactile stimulated by running an explorer and measured using VAS (1–10 scale); air blast and cold water stimulated hypersensitivity measured using the Schiff Sensitivity Scale at baseline, immediately, 15 days and 30 days after application. Friedman test and Wilcoxon test were used for within group comparisons. Kruskal–Wallis test and Mann–Whitney U test were used for between group comparisons.Results: All three groups showed significant reductions in hypersensitivity from baseline at all time points (p < 0.05). ProArginTM paste elicited a significantly higher reduction in hypersensitivity (p < 0.016) compared to Gluma and NovaMin� for all stimuli at the end of 30 days.Conclusions: A single topical application of ProArginTM paste is significantly more effective than both a single topical application of Gluma and NovaMin paste in relieving dentinal hypersensitivity immediately and over 30 days

Item Type: Article
Uncontrolled Keywords: Arginine; Dentinal hypersensitivity; Gluma; Instant desensitization; NovaMin; ProArgin
Subjects: Dentistry > MCODS Manipal > Preventive and Community Dentistry
Depositing User: KMC Library
Date Deposited: 06 Mar 2018 03:44
Last Modified: 06 Mar 2018 03:44
URI: http://eprints.manipal.edu/id/eprint/150687

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