Khadilkar, Urmila N and *, Sridevi H.B. and Prabhu, Laxman G.G and Tapadia, Rohit and *, Rakesh BH (2018) Mixed epithelial and stromal tumor – A solid‑cystic renal neoplasm undergoing malignant transformation: A rare case report. Indian Journal of Pathology and Microbiology, 61 (1). pp. 123-126. ISSN 03774929

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Abstract

We present a case of 53‑year‑old female who came with the complaints of mass on the right side of the abdomen noticed 3 weeks back. There was no history of localized swelling or rise of temperature, no history of weight loss, or evening rise of temperature. On examination, there was a flank mass which was bimanually palpable and tender. Routine laboratory investigations were within normal limits, except for the presence of hematuria in routine urinalysis. Computed tomography scan abdomen revealed a large multiloculated solid‑cystic mass lesion with septation in the right‑sided kidney. Cystic renal cell carcinoma was suspected and conventional open right radical nephrectomy was done. Grossly, the tumor was solid‑cystic containing blood‑tinged fluid. Microscopy revealed a complex tumor with both epithelial and stromal proliferation and with the aid of immunohistochemistry a diagnosis of mixed epithelial and stromal tumor undergoing malignant transformation was concluded.

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