Epithelioid leiomyosarcoma: a rare uterine cancer

Rekha, Upadhya and Poojari, Vidyashree G and Pai, Muralidhar V and Nambiar, Jayaraman (2018) Epithelioid leiomyosarcoma: a rare uterine cancer. International Journal of Reproduction, Contraception, Obstetrics and Gynecology, 7 (4). pp. 1663-1666. ISSN 2320-1770

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A uterine epithelioid leiomyosarcoma is a rare malignant tumour that arises from the smooth muscle lining the walls of the uterus. The exact cause of leiomyosarcoma, including uterine leiomyosarcoma accounting for 5 to 10% is unknown. Leiomyosarcoma is the most common subtype of uterine sarcoma, accounts for 1-2% of uterine malignancies. Malignancy should be suspected in menopausal women with tumour growth who are not on hormonal replacement therapy. A 64-year-old female had attained menopause 16 year back and developed postmenopausal bleeding since 2 months, with palpable mass, of 16 weeks size. Ultrasonography showed whorled mass lesions, endometrium and myometrium could not be seen separately. Uterus with both ovaries removed. Intra-operative findings showed 16 weeks uterine mass with size 15×10.5×10cm and weight 1kg with intramural fibroid. Necrotic and haemorrhagic areas with degenerative changes seen on cut section suggestive of malignancy. Histopathology and immunohistochemistry reported epithelioid leiomyosarcoma.

Item Type: Article
Uncontrolled Keywords: Epithelioid; Immunohistochemistry; Leiomyosarcoma; Postmenopause.
Subjects: Medicine > KMC Manipal > Obstetrics & Gynaecology
Depositing User: KMC Library
Date Deposited: 17 May 2018 04:46
Last Modified: 17 May 2018 04:46
URI: http://eprints.manipal.edu/id/eprint/150956

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