Evaluation of supportive care management outcomes in cancer chemotherapy: a prospective observational study in a tertiary care teaching hospital in south India

Reji, Reshma Susan and Kumar, Binit and Sreedharan, N and Thunga, Girish and Vijayanarayana, K and Rao, Mahadev and Udupa, Karthik S (2018) Evaluation of supportive care management outcomes in cancer chemotherapy: a prospective observational study in a tertiary care teaching hospital in south India. Indian Journal of Palliative Care, 24 (2). pp. 179-183. ISSN 0973-1075

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Abstract

Aims: Evaluation of supportive care management of cancer patients experiencing drug‑related problems (DRPs) is a challenge because it might increase the cost due to additional therapy. The main objectives of this study were to estimate chemotherapy‑associated drug‑related hospital admissions in the department of medical oncology and to estimate the cost of managing chemotherapy‑associated DRPs. Settings and Design: This study is a prospective observational study. Subjects and Methods: Patients with chemotherapy‑related DRPs were prospectively identified from the patient’s medical records. The contribution of DRPs and cost incurred due to each hospitalization was assessed. Statistical Analysis Used: Data were analyzed using SPSS® 20.0 version. Results: Out of 55 patients analyzed for DRPs, 25 (45.5%) patients in the age group of 51–60 years experienced DRPs most frequently. Most commonly occurring DRP was adverse drug reactions 42 (76.4%), which were more frequent in females. DRPs were maximum with alkylating agents 15 (27.3%) and the least with hormonal agents 1 (1.8%). The mean length of hospitalization was 9.6 ± 6.5 days. The total direct medical cost was Rs. 31,540 ± 42,476, of which medicine cost accounted for Rs. 16,550 ± 25,404, constituting a major share of the total medical costs. Conclusions: Pharmacists can provide better patient care by identifying and preventing DRPs and reducing drug‑related morbidity and mortality.

Item Type: Article
Uncontrolled Keywords: Adverse drug reactions; chemotherapy; drug‑related problems; supportive care.
Subjects: Medicine > KMC Manipal > Medical Oncology
Pharmacy > MCOPS Manipal > Pharmacy Practice
Depositing User: KMC Library
Date Deposited: 22 May 2018 06:45
Last Modified: 22 May 2018 06:45
URI: http://eprints.manipal.edu/id/eprint/151037

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