Phyllodes Tumor – A Clinicopathological Study

Benakatti, Rajendra and Tubachi, Prashant and Prabhu, Raghunath and Shenoy, Rajgopal (2016) Phyllodes Tumor – A Clinicopathological Study. IOSR Journal of Dental and Medical Sciences, 15 (3). pp. 33-37. ISSN 2279-0861

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Abstract

Phyllodes tumor are biphasic breast tumors occurring usually in adult females and are composed of benign epithelial component and a cellular spindle cell stroma forming leaf like structure. Diagnosis is based on clinical examination, mammography/sonography and FNAC but final diagnosis is based on histological findings. Benign tumors are treated by lumpectomy while recurrent tumors, malignant tumors and massive tumor require mastectomy without axillary dissection. This is a retrospective and prospective study, involving all biopsy proven cases of phyllodes tumor admitted to a tertiary care hospital in Udupi district during the period of January 2007 to June 2013. A total number of 30 cases of phyllodes tumor were reported in the study period from January 2007 to June 2013. Incidence rate is 1.42 among primary breast malignancy. Out of the 30 cases 20 were primary cases, 10 cases already underwent some form of surgery outside before presenting to our hospital. Mean age is 37.43 yrs., 30 cases (100%) presented with lump in breast and only 6 cases (20%) presented with pain associated with the lump. Mean tumor size was 8.1cms and standard deviation of 5.326cms. FNAC was done in 14 patients of which 7 were reported as phyllodes tumor, Trucut done in 7 cases 6 of which were suggestive of phyllodes tumor, slides and blocks from outside were reviewed and 2 cases were phyllodes tumor. FNAC of 1 case was reported as phyllodes done outside. No preoperative investigations were done in 4 cases. Majority of the patients (46.67%) underwent wide local excision followed by lumpectomy and mastectomy (23.33%) followed by simple mastectomy (6.67%). Final HPE reported as benign (66.67%), malignant is 20% and borderline is 13.33%. 8 cases (26.67%) have recurrence (4 of which had been operated previous outside our hospital) and no recurrence among 22 cases (73.33%). Phyllodes tumor is a rare tumor with high chances of recurrence need to be correctly diagnosed pre-operatively and wide local excision would the ideal choice of surgical treatment.

Item Type: Article
Uncontrolled Keywords: Phyllodes; Cystosarcoma; Clinicopathological study; Breast tumour
Subjects: Medicine > KMC Manipal > Surgery
Depositing User: KMC Library
Date Deposited: 06 Jun 2018 06:24
Last Modified: 06 Jun 2018 06:24
URI: http://eprints.manipal.edu/id/eprint/151243

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