Morphometric analysis of peripapillary thickness in hypertensives and normotensives using optical coherence tomography (OCT)

Rao, Krishna A and Bhandary, Sulatha V and Kapoor, Smita (2016) Morphometric analysis of peripapillary thickness in hypertensives and normotensives using optical coherence tomography (OCT). Journal of Clinical and Diagnostic Research, 10 (7). NC01-NC04. ISSN 0973-709X

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Abstract

Introduction: Hypotension following antihypertensive treatment is associated with retinal nerve fibre loss. There are studies that have reported the changes in RNFL in hypertensives.Aim: To compare the Retinal Nerve Fibre Layer (RNFL) thickness using Optical Coherence Tomography (OCT) in hypertensive and normotensive individuals.Materials and Methods: The cross-sectional study was conducted from October 2012 to September 2014 to compare the RNFL thickness using SD OCT in hypertensive {no other ocular or systemic co-morbidity, vision better or equal to 6/9 (n=30)} and normotensive (n=30) individuals. Results: Statistically significant RNFL loss was detected in hypertensives (98.31 ± 7.01) when compared to the normotensives (102.51 ± 8.72) p=0.001. Conclusion: Significant loss of RNFL in hypertensives point towards the altered autoregulation and warrants larger studies to assess the clinical relevance.

Item Type: Article
Uncontrolled Keywords: Hypertensive versus normotensives; Intra ocular pressure; OCT RNFL loss.
Subjects: Medicine > KMC Manipal > Ophthalmology
Depositing User: KMC Library
Date Deposited: 09 Oct 2018 04:20
Last Modified: 09 Oct 2018 04:20
URI: http://eprints.manipal.edu/id/eprint/152118

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