Mesoporous Silica Particles For Dermal Drug Delivery: A Review

Chsai, Sanjay and Ghate, Vivek M and Lewis, Shaila A (2018) Mesoporous Silica Particles For Dermal Drug Delivery: A Review. International Journal of Applied Pharmaceutics, 10 (6). pp. 23-26. ISSN 0975-7058

[img] PDF
5419 DisplayPdf.pdf - Published Version
Restricted to Registered users only

Download (359kB) | Request a copy


Mesoporous silica particles (MSP) have been reported to be applicable in diverse situations pertaining to the delivery of several drug molecules. MSP have established themselves in treating diseases with oral, dermal and parenteral modes of administration. Recently, dermal delivery using MSP have gained a considerable amount of interest owing to the increase in drug stability, permeation and ease of functionalization. MSP, in general, have a very high capability of delivering actives ranging from small molecules like drugs and amino acids to larger peptides, vaccines and antibodies. The applicability of MSP in achieving desired cosmetic and health-related outcomes depends on the careful tuning of their pore size, surface area, shape and overall physicochemical properties. This review provides comprehensive details of the recent developments in the fabrication of MSP, their characteristic features and, applications in dermal drug delivery. Studies on establishing the safety profile of MSP have also been summarized in the review.

Item Type: Article
Uncontrolled Keywords: Mesoporous Silica; Dermal Delivery; Permeation; Pore Size; Functionalization
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Library
Date Deposited: 30 Nov 2018 09:03
Last Modified: 30 Nov 2018 09:03

Actions (login required)

View Item View Item