Prabhu, Smitha S and Ravi, Deepthi and Shenoi, Shrutakirthi D and Pai, Kanthilatha and Nayak, Sudhir UK (2018) Multiple autoimmune syndrome with isotopic phenomenon: association of lichen planus, vitiligo and alopecia areata with autoimmune hepatitis. Journal of Pakistan Association of Dermatologists, 28 (3). pp. 356-359. ISSN 1560-9014

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Abstract

Multiple autoimmune syndrome (MAS) is the presence of 3 or more autoimmune disorders in the same patient, and is being increasingly reported. Here, we report a 31-year-old man who presented with lichen planus, vitiligo, alopecia areata and hepatitis. He also displayed isotopic phenomenon in the form of depigmented lichen planus lesions. Autoimmune tautology is implicated as the basis for MAS, and is supported by the findings of poly autoimmunity and familial immunity in crosssectional studies. There are reports of dermatological and systemic autoimmune diseases cooccurring as MAS.

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