Malaria Severity in Mangaluru City in the Southwestern Coastal Region of India

Dayanand, Kiran K and Punnath, Kishore and Chandrasheka, Valleesha and Achur N, Rajeshwara and Ghosh, Susanta K and Kakkilaya B, Srinivas and Kumari N, Suchetha and Tiwari, Satyanarayan and Boloor, Archith and Devi, Rajeshwari and Gowda D, Channe (2019) Malaria Severity in Mangaluru City in the Southwestern Coastal Region of India. American Journal of Tropical Medicine and Hygiene, 100 (2). pp. 275-279. ISSN 0002-9637

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Abstract

Dakshina Kannada district in the Southwestern region of Karnataka state, India, including Mangaluru city is endemic to malaria. About 80% of malaria infections in Mangaluru and its surrounding areas are caused by Plasmodium vivax and the remainder is due to Plasmodium falciparum. Malaria-associated clinical complications significantly occur in this region. Here, we report the pathological conditions of 41 cases of fatal severe malaria, admitted to the district government hospital in Mangaluru city during January 2013 through December 2016. The results of clinical, hematological, and biochemical analyses showed that most of these severe malaria cases were associated with thrombocytopenia, anemia, metabolic acidosis, acute respiratory distress, and single or multi-organ dysfunction involving liver, kidney, and brain. Of the 41 fatal malaria cases, 24, 10, and seven patients had P. vivax, P. falciparum, and P. vivax and P. falciparum mixed infections, respectively. These data suggest that besides P. falciparum that is known to extensively cause severe and fatal malaria illnesses, P. vivax causes fatal illnesses substantially in this region, an observation that is consistent with recent findings in other regions.

Item Type: Article
Uncontrolled Keywords: Malaria, India, Mangaluru, Plasmodium vivax, Plasmodium falciparum, Admission, Severe, Fatal
Subjects: Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 14 Feb 2019 10:38
Last Modified: 14 Feb 2019 10:38
URI: http://eprints.manipal.edu/id/eprint/153281

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