Allium sativum: A substitute to chlorhexidine in dental hygiene?

Purandare, Mrudgandha and Shenoy, Padmaja Ananth and Khan, Saleemulla and Anegundi, Renuka and Vishwanath, Shashidhar and Chawla, Kiran (2018) Allium sativum: A substitute to chlorhexidine in dental hygiene? Asian Journal of Microbiology, Biotechnology & Environmental Sciences, 20 (2). S270-S274. ISSN 0972-3005

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Dental hygiene is essential for general health and well-being of life. Garlic (Allium sativum) which is being used as a flavoring agent, is known to have antibacterial, antiviral and antifungal activity. A study was conducted to determine the antimicrobial activity of an alcoholic extract and standardized juice of Allium sativum on different periodontal pathogens such as Streptococcus mutans, Porphyromonas gingivalis, Prevotella bivia, Fusobacterium nucleatum and Candida albicans. The fresh juice & ethanolic extract of garlic were prepared and divided in to various concentrations (20%, 40%, 60% and 80%). The standardization of fresh garlic juice was carried out by High Performance Thin Layer Chromatography (HPTLC). The antimicrobial activity was determined against periodontal isolates by agar well and disc diffusion method as per standard guidelines. The fresh garlic juice showed excellent antibacterial and antifungal activity in our study by agar well diffusion method and results were better than chlorhexidine control. Hence fresh garlic juice may be used as an alternative for chlorhexidine in dental diseases.

Item Type: Article
Uncontrolled Keywords: Allium sativum; Antimicrobial activity; Chlorhexidine; Agar well diffusion; HPTLC.
Subjects: Medicine > KMC Manipal > Microbiology
Pharmacy > MCOPS Manipal > Pharmacognosy
Depositing User: KMC Library
Date Deposited: 20 Mar 2019 03:44
Last Modified: 20 Mar 2019 03:44

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