An update on possible pathogenic mechanisms of periodontal pathogens on renal dysfunction

Chopra, Aditi and Sivaraman, Karthik (2019) An update on possible pathogenic mechanisms of periodontal pathogens on renal dysfunction. Critical Reviews in Microbiology. pp. 1-25. ISSN 1040-841X

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Abstract

Periodontitis is a potential source of permanent systemic inflammation that initiates renal dysfunction and contributes to the development of chronic kidney diseases (CKDs). Although numerous studies have confirmed the bidirectional role of periodontal infection and renal inflammation,no literature has yet highlighted the sophisticated pathogenic mechanisms by which periodontal pathogens, particularly Porphynomonas Gingivalis, induce renal dysfunction and contributed in the development of CKDs. The present review aims to critically analyze and highlight the novel pathogenesis of periodontitis induced CKDs.

Item Type: Article
Uncontrolled Keywords: Chronic kidney diseases;End-stage renal disease;Inflammation;Periodontitis;Porphyromonas gingivalis
Subjects: Dentistry > MCODS Manipal > Prosthodontics
Dentistry > MCODS Manipal > Periodontology
Depositing User: KMC Library
Date Deposited: 02 Apr 2019 11:12
Last Modified: 02 Apr 2019 11:12
URI: http://eprints.manipal.edu/id/eprint/153576

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