Bhat, Shashikala K and Umakanth, Shashikiran and Shah, Krupa H and Ashwini, AP and Prabhu, Ravindra A (2018) Childhood onset nephrotic syndrome-a journey through two pregnancies. Journal of Clinical and Diagnostic Research, 12 (7). QD08-QD09. ISSN 0973-709X

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Abstract

Nephrotic Syndrome (NS), a unique renal disease complex associated with heavy proteinuria (protein excretion >3.5 gm/day), hypoalbuminemia (<30 gm/L) and peripheral oedema. It is a rare entity in pregnancy, with an incidence of about 0.012-0.025%. There have been very few reports of pregnancy with co-existing NS. We hereby report a case of steroid sensitive childhood onset NS, due to minimal change disease and her course through two pregnancies. While she had a relapse of NS during her first pregnancy, she sailed through her second pregnancy without relapse. Women with NS can have a good maternal and perinatal outcome with multidisciplinary approach. Pregnancy does not always worsen the existing NS by causing a relapse or disease progression.

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