Natural articular cartilage: A smart biointerface

Pawlak, Zenon and Pai, Raghuvir B and Mrela, A and Kaczmarek, M and Yusuf, Kehinde Q. and Urbaniak, Wieslaw (2019) Natural articular cartilage: A smart biointerface. Journal of Computational Methods in Sciences and Engineering, 19. pp. 479-489. ISSN 1472-7978

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Abstract

In healthy joints, the cartilage surface coated with phospholipid multi-bilayers is governed by the lamellar-repulsive hydration mechanism. The phospholipid bilayers of biological surface are investigated by friction testing, while surface degradation is controlled by wettability. This paper proposes the presence of cartilage surfaces that are negatively charged results in highly efficient lubrication in natural joints. At pH �7.4, the mechanism of lamellar-repulsion between contacting cartilage surfaces is supported by charged macromolecules of synovial fluid and phospholipid lamellar phases. It was proven experimentally that phospholipid (PLs) bilayers with lamellar structure can act as an effective solid lubricant in friction and wear under biological test conditions

Item Type: Article
Uncontrolled Keywords: Fixed charge density, friction coefficient, lamellar-repulsive hydration lubrication, wettability of synovial joint
Subjects: Engineering > MIT Manipal > Mechanical and Manufacturing
Depositing User: MIT Library
Date Deposited: 24 May 2019 09:24
Last Modified: 24 May 2019 09:24
URI: http://eprints.manipal.edu/id/eprint/153866

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