Primary laryngeal amyloidosis: A case report

Tewari, Siddharth and Mathew, Mary (2017) Primary laryngeal amyloidosis: A case report. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 8 (5). pp. 620-624. ISSN 0975-8585

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Primary laryngeal amyloidosis is a rare entity, but is the commonest site for deposits of amyloid in head and neck. A 59 years old healthy adult, a known case of allergic rhinosinusitis and chronic proximal nocturnal dyspnea came to the hospital with complaint of hoarseness of voice for the past 3 months. On examination the posterior pharyngeal wall appeared granular. Indirect laryngoscopy revealed edematous ventricular bands (Right< Left) .Mobility of vocal cords was not affected. A proliferative growth was noticed to be arising from the anterior 2/3rd of the left vocal cord. A biopsy of the lesion was taken that showed no evidence of malignancy of larynx. Two weeks later, the patient underwent repeat biopsy from left false cord growth under general anesthesia. Histopathological examination revealed amyloidosis in left false cord. Clinical presentation of the laryngeal amyloidosis often mimics neoplasm of larynx and so, a high degree of suspicion is required. Excision of the lesion with CO2 laser is the treatment of choice.

Item Type: Article
Uncontrolled Keywords: Larynx; hoarseness; amyloidosis.
Subjects: Medicine > KMC Manipal > Pathology
Depositing User: KMC Library
Date Deposited: 19 Jul 2019 04:21
Last Modified: 19 Jul 2019 04:21

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