Periodontal diseaseandhemolysisinglucose-6-phosphate dehydrogenasedeficiency:Isthereanexus?

Singh, Neelesh and Uppoor, Ashita .S. and *, Valliammai Rajendran and Nayak, Dilip .G. (2019) Periodontal diseaseandhemolysisinglucose-6-phosphate dehydrogenasedeficiency:Isthereanexus? Journal of Oral Biosciences, 61 (2019). pp. 129-133. ISSN 13490079

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Abstract

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an erythrocyte enzyme defect that amplifies the susceptibility of erythrocytes to oxidative stress due to excessive levels of reactive oxygen species. Consequently, erythrocyte destruction and hemolysis occur. Highlight: The possible mechanism of oxidative stress-mediated destruction of erythrocytes in G6PD deficient individuals induced by periodontal infection is highlighted. Conclusion: Periodontal diseases feature systemic loading of reactive oxygen species, and they may increase the risk of hemolysis in individuals with G6PD deficiency.

Item Type: Article
Uncontrolled Keywords: Periodontal infection Oxidativestress Hemolysis
Subjects: Dentistry > MCODS Mangalore > Periodontics
Depositing User: KMCMLR User
Date Deposited: 03 Jul 2019 04:05
Last Modified: 03 Jul 2019 04:05
URI: http://eprints.manipal.edu/id/eprint/154077

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