Total phenolic and flavonoid content, antioxidant effects and antidiarrheal activity of balacaturbhadrika churna – an Ayurvedic preparation

Pratap, Rahul and Ram, Aswatha HN and Chandrashekar, KS and Pai, Vasudev and Kamath, Venkatesh (2019) Total phenolic and flavonoid content, antioxidant effects and antidiarrheal activity of balacaturbhadrika churna – an Ayurvedic preparation. Indian Journal of Traditional Knowledge, 18 (3). pp. 485-492. ISSN 0972-5938

[img] PDF
00006942.pdf - Published Version
Restricted to Registered users only

Download (230kB) | Request a copy

Abstract

Balacaturbhadrika churna (BC) is an important pediatric preparation in Ayurveda. It is used to treat various diseases of gastro-intestinal tract particularly diarrhea in children. Free radicals cause oxidative damage in the intestine and are correlated with its diseases. In the current study, total phenolic and flavonoid contents of BC extracts were determined and their antioxidant evaluation in various in vitro models was carried out. Procedures mentioned in The Ayurvedic Formulary of India were followed to prepare in-house BC; alcoholic (BCAL) and aqueous (BCAQ) extracts were prepared and tested by standard procedures. BCAL was tested for antidiarrheal activity in castor oil induced model. The ethanolic extract showed better antioxidant activity in many of the models as compared to aqueous extract. The present study showed substantial amounts of flavonoids and phenolics in churna extracts. BCAL showed significant antidiarrheal activity against the tested model. The potential antioxidant and antidiarrheal activities displayed by Balacaturbhadrika churna extracts could be attributed to these contents.

Item Type: Article
Uncontrolled Keywords: ABTS ;Antidiarrheal ;Antioxidant ;Balacaturbhadrika churna ;DPPH;Flavonoid ;Phenolic.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Biotechnology
Pharmacy > MCOPS Manipal > Pharmacognosy
Depositing User: KMC Library
Date Deposited: 31 Jul 2019 08:45
Last Modified: 31 Jul 2019 08:45
URI: http://eprints.manipal.edu/id/eprint/154225

Actions (login required)

View Item View Item