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Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An Experiment on Cadmium Exposed Rats

*, Vinodini N.A and Chatterjee, Pratik Kumar and *, Kunal and *, Suman VB and *, Rashmi KS and *, Nayanatara AK and *, Anupama N and Bhat, Ramesh M and Joice P, Sheela (2019) Effectiveness of Moringa oleifea Extract in Attenuating the Toxic Effect on Platelet Count: An Experiment on Cadmium Exposed Rats. Pharmacognosy Journal, 11 (4). pp. 689-693. ISSN 09753575

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Abstract

Aims and Objective: To determine the role of Moringa oleifera on total platelet count alterations (T-PC) in rats treated with cadmium. Materials and Methods: In the present study female adult Wistar Albino rats, (180-200) gm were divided into, Group I-normal control, Group II-pretreated control, group III-cadmium treated , group IV- pre-treated with Moringa oleifera leaf extract (MOE) and then administered oral cadmium for a day, with n=6 each RESULTS : Indicate that the pre-treatment with MOE (100 mg/kg/bw) prior to cadmium infusion augmented the level of total platelet count (p≤0.001) as compared to the cadmium-exposed group, which might have a role in clotting mechanisms also. Conclusion: Moringa oleifera extract has a beneficial effect on platelet count in cadmium-induced animal model.

Item Type: Article
Uncontrolled Keywords: Cadmium, Platelet count, Clotting mechanisms, Toxicity, Moringa oleifera.
Subjects: Medicine > KMC Mangalore > Physiology
Depositing User: KMCMLR User
Date Deposited: 24 Jul 2019 08:58
Last Modified: 24 Jul 2019 08:58
URI: http://eprints.manipal.edu/id/eprint/154267

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