Oral nodular fasciitis – A case report with a diagnostic schema

Rathna, Deepika and Mathew, Mary and Kudva, Adarsh and Solomon, Monica C (2019) Oral nodular fasciitis – A case report with a diagnostic schema. Journal of Oral Medicine and Oral Surgery, 25 (2). pp. 1-5. ISSN 2608-1326

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Introduction: The spectrum of myofibroblastic lesions of the oral cavity ranges from reactive to benign to malignant lesions with overlapping histopathologic and immunohistologic characteristics posing a diagnostic dilemma. Observation: A 30-year-old male presented with a spontaneous swelling over the right lower buccal gingiva giving a clinical suspicion of a benign mesenchymal tumor. The lesion presented with a varied biphasic microscopic appearance that posed as a challenge for diagnosis. Commentaries: The incisional biopsy of the lesion showed a highly collagenous stroma with spindle-shaped cells, while the excision biopsy revealed myxoid and hyalinized stroma. A panel of markers comprising of SMA (smooth muscle actin). CD-34, b-Catenin, and Alcian blue stain was employed to arrive at a diagnosis. Conclusion: Most myofibroblastic lesions present with diverse histological appearance which warrants a thorough assessment of the cellular and stromal components for an accurate diagnosis.

Item Type: Article
Uncontrolled Keywords: Spindle cells; nodular fasiitis; myofibroblasts; myxoid degeneration; myofibroma.
Subjects: Dentistry > MCODS Manipal > Oral and Maxillofacial Surgery
Dentistry > MCODS Manipal > Oral Pathology and Microbiology
Medicine > KMC Manipal > Pathology
Depositing User: KMC Library
Date Deposited: 17 Aug 2019 05:34
Last Modified: 17 Aug 2019 05:34
URI: http://eprints.manipal.edu/id/eprint/154368

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