Prognostic Factors in Patients with Sepsis Synrome

Shenoy, Ashok. K and Adhikari , Prabha. MR and Chowta, Mukta N. and Ullal, Sheetal D and *, Gopalakrishna HN and *, Rathnakar UP and *, Sudhakar P and *, Unnikrishnan B (2011) Prognostic Factors in Patients with Sepsis Synrome. Pharmacologyonline, 2. pp. 854-858.

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Abstract

Septicemia is a leading cause of mortality in hospitalized patients. The septic response is now a contributing factor in more than 1,00,000 deaths per year in the United States. Incidence of sepsis is increasing due to increase in the risk factors such as comorbid conditions like diabetes mellitus, immunocompromised status of patients etc. Objective of the study is to describe the clinico-demographic profile and to identify the factors which affect the prognosis in patients suffering from sepsis syndrome. The charts of sixty consecutive patients admitted in a tertiary care hospital were analyzed. Out of sixty patients 20 survived. Higher mortality as age increases was found statistically significant. Co morbid conditions also contributed significantly to mortality. Most common organism was staphylococci. Admissions in ICU or number of days in the ICU were not significantly associated with outcome. Cephalosporins were the most common antimicrobial agent prescribed. Most important finding of the study is the statistically significant relationship between comorbid conditions like diabetes mellitus and mortality due to sepsis syndrome. Respiratory infection as a source of infection also seen to adversely affect the outcome. Most common organism associated with sepsis syndrome was staphylococci, though the finding was statistically not significant

Item Type: Article
Uncontrolled Keywords: Sepsis, Mortality, septic shock, sepsis syndrome, septicemia
Subjects: Medicine > KMC Mangalore > Pharmacology
Medicine > KMC Mangalore > Community Medicine
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 17 Oct 2011 06:12
Last Modified: 17 Oct 2011 06:12
URI: http://eprints.manipal.edu/id/eprint/1545

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