Effect of Probiotics on Dental Caries and Periodontal Pathogens: An In Vitro Study

Routh, Subhajit and Pai, Mithun B.H. and *, Rajesh G and Shenoy, Ramya and Sarit, Swapna (2019) Effect of Probiotics on Dental Caries and Periodontal Pathogens: An In Vitro Study. Journal of Orofacial Sciences, 11 (1). pp. 49-54. ISSN 09758844

[img] PDF
Effect of Probiotics on Dental Caries and Periodontal Pathogens An In Vitro Study.pdf - Published Version
Restricted to Registered users only

Download (615kB) | Request a copy

Abstract

Introduction:Probiotics are microorganisms that are administered in live forms and can improve healthand well being of human beings. Literature about their antimicrobial activity against oral pathogens islimited. The present study was conceptualized to ascertain the antimicrobial capabilities of commonprobiotics against microorganisms involved in dental caries and periodontal diseases. The aim of thisarticle is to ascertain the action of probiotics on dental caries pathogen,Streptococcus mutans, andperiodontal microbes that includedPorphyromonas gingivalis,Actinobacillus actinomycetemcomitans,andPrevotella intermedia.Materials and Methods: The present study was anin vitrotype of study.A.actinomycetemcomitanswas cultivated in tryptic soy-serum-bacitracin-vancomycin-fluoride agar,Po.gingivalisin modified Wilkins–Chalgren medium, andPr. intermediain brain heart infusion agar. Thesamples were cultivated for 48 h in Brewer-like anaerobic jars. The first plate was impregnated withstrains of the probioticLactobacillus acidophilus, the second plate with strain of the probioticS.salivarius, and the third plate was kept as the control. Zones of inhibition were calculated by unaided eyeemploying a Vernier caliper to the nearest millimeter, including the diameter of the disk in themeasurement.Results: Analysis of variance test exhibited significant findings at 24 and 48 h.Post hocTukey test revealed results that were statistically significant for all microorganisms but forA. actino-mycetemcomitansandPr. intermedia.Conclusion: The findings showed significant effect of probioticson common microbes implicated in dental caries and periodontal diseases. The present study has crucialpublic health implications for the prevention and control of common oral diseases in populations.

Item Type: Article
Uncontrolled Keywords: Dental caries, in vitro techniques, oral health, periodontal diseases, probiotics
Subjects: Dentistry > MCODS Mangalore > Public Health Dentistry
Depositing User: KMCMLR User
Date Deposited: 09 Sep 2019 06:27
Last Modified: 09 Sep 2019 06:27
URI: http://eprints.manipal.edu/id/eprint/154503

Actions (login required)

View Item View Item