Breast cancer and the heart: burden on the chest

Singh, Jora and Kareem, Hashir and Devasia, Tom and Khera, Kanav and Chauhan, Sheetal and Rao, Yeswanth and Pai, Ganesh (2018) Breast cancer and the heart: burden on the chest. Journal of Cardiovascular Disease Research, 9 (1). pp. 1-4. ISSN 0975-3583

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Breast cancer survivors after successful treatment face various complications in their life. These problems are related to their psycho-social life and/or related to altered body image or may be because of the side effects of breast cancer therapy. Different types of treatment show various hemodynamic/physiological changes on one or more organ/systems. Cardiovascular is the mainly affected system after breast cancer treatment. Radiation-induced heart diseases (RIHD) involve a broad cardiac pathology comprising myocardial fibrosis and cardiomyopathies, pericardial disease, valvular heart diseases, arrhythmias and coronary artery diseases. Chemotherapy induced cardiotoxicity (CIC) affects the morbidity and mortality in breast cancer survivors. Regardless of cancer prognosis; it impacts the quality of life and overall survival with major limitations in life. Conventional diagnostic procedures and biomarkers can be used to detect RIHD and CIC. Cardio-oncology helps in filling the gap between cardiologist and oncologist to reduce the future cardiac risk in survivors.

Item Type: Article
Uncontrolled Keywords: Radiotherapy induced heart disease (RIHD); Chemotherapy induced cardiotoxicity (CIC); Modified radical mastectomy (MRM); Ultrasound tissue characterization (UTC); Myocardial fibrosis.
Subjects: Medicine > KMC Manipal > Cardiology
Medicine > MMMC Manipal > Pharmacology
Pharmacy > MCOPS Manipal > Pharmacy Practice
Depositing User: KMC Library
Date Deposited: 25 Sep 2019 09:30
Last Modified: 25 Sep 2019 09:30

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