C‑type lectin family XIV members and angiogenesis (Review)

Borah, Supriya (2019) C‑type lectin family XIV members and angiogenesis (Review). Oncology Letters, 18. pp. 3954-3962. ISSN 1792-1074

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Abstract

The growth and metastasis of tumors is dependent on angiogenesis. C‑type lectins are carbohydrate‑binding proteins with a diverse range of functions. The C‑type lectin family XIV members are transmembrane glycoproteins, and all four members of this family have been reported to regulate angiogenesis, although the detailed mechanism of action has yet to be completely elucidated. They interact with extracellular matrix proteins and mediate cell‑cell adhesion by their lectin‑like domain. The aim of the present study was to summarize the available information on the function and mechanism of C‑type lectin family XIV in angiogenesis and discuss their potential as targets for cancer therapy.

Item Type: Article
Uncontrolled Keywords: C‑type lectin family XIV; angiogenesis; CLEC14A; thrombomodulin; CD93; endosialin.
Subjects: Life Sciences > MLSC Manipal
Depositing User: KMC Library
Date Deposited: 12 Feb 2020 05:39
Last Modified: 12 Feb 2020 05:39
URI: http://eprints.manipal.edu/id/eprint/154875

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