The therapeutic potential of Curcumin: a review of clinical trials

Salehi, Bahare and Stojanović-Radic, Zorica and Matejić, Jelena and Sharif-Rad, Mehdi and Anil Kumar, N V and Martins, Natália and Sharif-Rad, Javad (2019) The therapeutic potential of Curcumin: a review of clinical trials. European Journal of Medicinal Chemistry. ISSN 0223-5234

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Abstract

Curcuma longa L., its derived extracts and even its major compound curcumin has a long history of use and doubtless effectiveness, reported through increasingly detailed in vitro, exvivo, in vivo and even clinical trials. Regarding its biological effects, multiple health-promoting, disease-preventing and even treatment attributes has been remarkably highlighted. Clinical trials, although have increased in a progressive manner, significant disproportionalities have been stated in terms of biological effects assessment. In this sense, the present report aims to provide an extensive overview to curcumin therapeutic effects in human subjects. For that, clinical trials assessing the curcumin effect on inflammation, skin, eye, central nervous system, respiratory, cardiovascular, gastrointestinal, urogenital and metabolic disorders are here presented and discussed. A special emphasis was also given to curcumin activity on intoxications and multiple malignant diseases.

Item Type: Article
Uncontrolled Keywords: Curcuma longa L.; Secondary metabolites; Curcuminoids; Pharmacological effects; Clinical trials
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 23 Jun 2020 05:48
Last Modified: 23 Jun 2020 05:48
URI: http://eprints.manipal.edu/id/eprint/155195

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