A comprehensive review of adult onset spinal teratomas: analysis of factors related to outcomes and recurrences

Prasad, Lakshmi G and Divya, S (2020) A comprehensive review of adult onset spinal teratomas: analysis of factors related to outcomes and recurrences. European Spine Journal, 29. pp. 221-237. ISSN 1432-0932

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Purpose Spinal teratomas are rare tumours noted in adults and are commonly located in the thoracolumbar region. Currently, there appears to be a lack of clear consensus regarding the management and prognosis of these lesions. A comprehensive review along with an illustrative case managed at the author’s institute has been presented.Materials and methods Online database search was performed for literature review.Results A 26-year-old male presented with acute onset neurological defcits and imaging revealed features ofconusteratoma. Subtotal resection was performed and patient achieved fair recovery. Including the present one, a total of 146 cases have been reported and were analysed. Mean age was 39.6 years (range 18–85 years) and males predominated. Limb weakness and backache were the commonest symptoms. Majority of the lesions were intramedullary and located inthe thoracolumbar region. Complete resection (CR) was achieved in 45% of cases. All, exceptone, were mature teratomas. Recurrences were noted in nine (6.1%) cases. Outcome wasgood/excellent in 86 (60%) and fair/poor in 26 (18%) cases. The presence of pain, absence of limb weakness and CR were signifcantly associated with good outcomes. Furthermore, subtotal resection (STR) had signifcantly higher recurrence rates than CR. Four deaths (2.7%) were noted.Conclusions Total surgical resection is the standard treatment and appears to be benefcial both in terms of outcomes and recurrences. Overall, recurrences are rare and may be managed by re-surgery. In addition, the present report is the eighth case of adult spinal teratoma with an acute onset presentation.

Item Type: Article
Uncontrolled Keywords: Teratoma;Mature teratoma ; Adult ; Spinal ; Spinal teratomas.
Subjects: Dentistry > MCODS Manipal > Orthodontics
Medicine > KMC Manipal > Neuro Surgery
Depositing User: KMC Library
Date Deposited: 02 Jul 2020 04:00
Last Modified: 02 Jul 2020 04:00
URI: http://eprints.manipal.edu/id/eprint/155196

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