Laparoscopic Management of Peritonitis Due to a Ruptured Ovarian Endometrioma with Extremely High Levels of Cancer Antigen–125 and Cancer Antigen–19-9

Pandey, Deeksha (2019) Laparoscopic Management of Peritonitis Due to a Ruptured Ovarian Endometrioma with Extremely High Levels of Cancer Antigen–125 and Cancer Antigen–19-9. Journal of Gynecologic Surgery, 35 (3). pp. 198-200. ISSN 1042-4067

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Abstract

Background: An endometrioma is a common gynecologic condition, usually defined as a growth of endometrial tissue outside the uterine cavity. Rarely, an ovarian endometrioma can rupture spontaneously, while the clinical significance of serum cancer antigen (CA)–125 and CA–19-9 levels might be that they are indicators of the presence of that endometrioma. Case: A 23-year-old nulliparous woman had acute abdominal pain with peritonitis. Computed tomography showed a left ovarian mass *12 cm with fluid collection in the intra-abdominal cavity and thickening of the omentum. These findings appeared to be ovarian cancer with ascites and omental caking. The patient’s CA-125 and CA–19-9 levels were 25,149 U/mL and 5379 U/mL, respectively. Results: A laparoscopic view showed a ruptured left ovarian endometrioma with diffused chocolate content over the surface of the liver, omentum, and intra-abdominal cavity. Laparoscopic enucleation of the left ovary, peritoneal irrigation, and adhesiolysis were performed. A pelvic mass score, such as a risk of malignancy index, could not be used to detect malignant ovarian cancer due to the patient’s high levels of CA-125 and CA–19-9. Conclusions: High combination CA-125 and CA–19-9 concentrations could indicate the presence of a ruptured endometrioma. Laparoscopy—performed by an experienced endoscopist—is an efficient procedure for con- firming a diagnosis and operating safely to remove the mass. ( J GYNECOL SURG 35:198)

Item Type: Article
Uncontrolled Keywords: Ruptured endometrioma; laparoscopy; CA-125; CA–19-9
Subjects: Medicine > KMC Manipal > Obstetrics & Gynaecology
Depositing User: KMC Library
Date Deposited: 03 Jul 2020 06:14
Last Modified: 03 Jul 2020 06:14
URI: http://eprints.manipal.edu/id/eprint/155264

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